David Bryan, M.D. 's Urology Blog

I get a lot of questions about this. Here is a link to a recent study which shows an increase in relative risk in those on Actos

http://www.epocrates.com/dacc/1207/pioglitazonebladdercancerBMJ1207.pdf

Conclusion: Those with Type 2 DM have an increased risk if taking Actos.